I'll catch channel cats while fishing for rockfish in the spring on the Potomac on a 8 or 9 weight with Cortland 350 gr quick descent line use a half and half. With a sinking line, I use a 4 foot bullwhip furled leader from Feathercraft and 3 feet of 20 lb flourocarbon.
Edit - Just checked the sticker on the spool it's a 325 gr line.
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